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Sylvia Agnes Sophia Tait
Sylvia Agnes Sophia Tait (8 January 1917 – 28 February 2003) (''née'' Wardropper, known as Sylvia Simpson from 1941 to 1956) was an English biochemist and endocrinologist. She worked with her second husband, James Francis Tait, from 1948 until her death in 2003, a partnership described by the Oxford Dictionary of National Biography as "one of the most successful examples of husband-wife scientific collaboration". Together, they discovered and identified the hormone aldosterone, the last of a series of naturally occurring biologically potent steroid hormones to be isolated and identified between the 1920s to the 1950s, after the androgens, oestrogens, and glucocorticoid hormones. Aldosterone is part of the mechanism that regulates blood pressure, and causes conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. It is thought to be responsible for 15 per cent of cases of high blood pressure.
==Early life==
Tait was born in Tyumen in Siberia, the daughter of Scottish agronomist and trader James Wardropper and his Russian wife Ludmilla. Unusually, her mother had obtained a degree in mathematics from the University of Moscow in Tsarist Russia.
She returned with her family to the UK in 1920, living in Ealing, and her father became a civil engineer. She was educated at Ealing County School for Girls, specialising in languages. She spoke fluent Russian, and improved her German by spending time with relatives in Germany before the Second World War. She suffered a knee injury playing netball at school, and later underwent three knee replacements.
She continued her language studies at King's College, London, and but then moved to University College London and graduated with a degree in zoology in 1939. She married Anthony Simpson, a fellow zoology student at University College London and a pilot with RAF Coastal Command, in 1940. He was killed in Norway in October 1941.
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